RESEARCH ARTICLE


A Bayesian Hierarchical Analysis of Geographical Patterns for Child Mortality in Nigeria



Rasheed A. Adeyemi1, *, Temesgen Zewotir2, Shaun Ramroop1
1 School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal,Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa
2 School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Westville campus, Durban, 4000, South Africa


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Creative Commons License
© 2019 Adeyemi et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, South Africa;
E-mail: adeyemira@yahoo.ca


Abstract

Background:

In an epidemiological study, disease mapping models are commonly used to estimate the spatial (or temporal) patterns in disease risk and to identify high-risk clusters, allowing for health interventions and allocation of the resources. The present study proposes a hierarchical Bayesian modeling approach to simultaneously capture the over-dispersion due to the effect of varying population sizes across the districts (regions), and the spatial auto-correlation inherent in the childhood mortality at districts (state) level in Nigeria.

Methods:

This cross-sectional study was based on 31842 children data extracted from the 2013 Nigeria Demographic and Health Survey (DHS). Of these children, 2886 died before reaching the age of five years. A Standardized Mortality Ratio (SMR) was estimated for each district (state) and mapped to highlight the risk patterns and detect an unusual low (high) clusters relative risk of childhood mortality. Generalized Poisson regression models were formulated with random effects to estimate the mortality risk and then explored to investigate the relationship of under-five child mortality and the regional risk factors. The random effects are formulated to reflect the potential tendency of “neighbouring” regions to have similar risk patterns and the spatial heterogeneity effect was used to capture geographical inequalities in the mortality outcomes. The models were implemented using a full Bayesian framework. All model parameters were estimated in WinBUGS via Markov Chain Monte Carlos (MCMC) simulation techniques.

Results:

The results showed that of the economically deprived households, 2.088: 95% CI (1.088, 3.165) were significantly associated with childhood mortality, while unhygienic sanitation and lack of access to improved water sources were positively associated with child mortality, but not statistically significant at 5% probability level. The geographical variation of the under-five mortality prevalence was found to be attributed to 69% clustering and 31% was due to spatial heterogeneity factors. The predicted probability maps identified clusters of high risk mortality in the northern regions and low prevalence of concentrated mortality in the south-west regions of Nigeria.

Conclusion:

The results demonstrated the flexibility of the approach that explored the geographical variation in the potential risk factors of child mortality and that it provides a better understanding of the regional variations of mortality risks. Nonetheless, both representations can help to provide information for the initiation of public health interventions.

Keywords: Child mortality, Poisson mixed model, Health geography, Spatial epidemiology, Geographical patterns, DHS.