Impact of Armed Conflicts on Neonatal Health: A Scoping Review

Armed conflicts threaten maternal and neonatal health, yet evidence on neonatal outcomes remains fragmented. This scoping review mapped evidence on armed conflict’s impact on neonatal health and identified pathways influencing outcomes.

This scoping review followed Arksey and O’Malley’s framework and PRISMA-ScR guidelines. MEDLINE/PubMed, Web of Science, Embase, Global Health (CABI), and CINAHL were searched, supplemented by Google Scholar and reference-list screening. Articles published from 2006 to 2025 reporting neonatal health outcomes (0-28 days) in conflict-affected settings were included. Maternal and pregnancy-related factors were considered when linked to neonatal outcomes. Twenty-nine articles were synthesized thematically.

Four overarching themes emerged: (1) war-driven neonatal adversity, (2) health system collapse impact, (3) risks associated with alternative and non-formal care practices, and (4) stress-associated biological and epigenetic changes. Armed conflict was associated with increased neonatal mortality, preterm birth, low birth weight, congenital anomalies, and neonatal morbidity. Pathways included violence exposure, healthcare disruption, displacement, food insecurity, environmental hazards, and maternal psychological stress.

Conflict affects neonatal health through interconnected biological, social, environmental, and health system pathways. Health system disruption, reduced access to skilled care, unsafe care practices, and maternal stress may compound adverse outcomes. Emerging evidence of epigenetic changes suggests potential longer-term consequences and underscores the need for integrated humanitarian and health system responses.

Priorities include strengthening health system resilience, ensuring continuity of maternal-newborn services, and integrating context-appropriate maternal mental health and psychosocial support. Further research should identify feasible, culturally responsive, and scalable interventions in underrepresented and protracted conflict settings.